2026-04-14T13:43:24Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/590802025-02-21T10:04:53Zcom_10324_1176com_10324_931com_10324_894col_10324_1359
Bello Gutierrez, Hugo José
Caballero García, Alberto
Pérez Valdecantos, Daniel
Roche Collado, Enrique
Noriega González, David César
Córdova Martínez, Alfredo
2023-04-11T12:51:17Z
2023-04-11T12:51:17Z
2021
Nutrients, 2021, Vol. 13, Nº. 11, 4013
2072-6643
https://uvadoc.uva.es/handle/10324/59080
10.3390/nu13114013
4013
11
Nutrients
13
2072-6643
Producción Científica
Vitamin D is a key micronutrient modulating function and health in skeletal muscle. Therefore, we sought to systematically review the role of vitamin D in muscle recovery. A search in different databases (PubMed/MEDLINE, WOS, Google Scholar, and Scopus) was carried out following PRISMA® and PICOS. The search period was from inception to April 2020. Changes in post-exercise muscle damage were quantified comparing experimental group vs. placebo in each study by using number of participants, standardized mean difference (SMD), and standard error of the SMD. Hedges’s g was used to calculate the SMDs for each study group and biased by the inverse of variance that allows calculating an overall effect and the 95% confidence interval (CI). The net vitamin D supplementation effect was calculated by subtracting the placebo SMD from SMD of the experimental group. The DerSimonian and Laird method was used as a random effect model, taking into account that the effect of vitamin D on muscular damage may vary according to the dose administered and additional moderators. Six studies were selected. In conclusion, regarding circulating levels of muscle biomarkers and additional limitations of the studies, it cannot be concluded that vitamin D supplementation exerts an effect in post-exercise muscle recovery. Likely, the anti-inflammatory action of vitamin D is quicker than the recovery of tissue structure and function. This aspect is pending verification in future research.
Instituto de Salud Carlos III - Fondo Europeo de Desarrollo Regional (CB12/03/30038)
application/pdf
eng
MDPI
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
© 2021 The authors
Atribución 4.0 Internacional
Creatine kinase
Ejercicio
Ejercicio físico
Vitamin D
Systematic reviews (Medical research)
Meta-analysis
Muscle damage
Myoglobin
Recovery
Effects of vitamin D in post-exercise muscle recovery. A systematic review and meta-analysis
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
https://www.mdpi.com/2072-6643/13/11/4013
SI