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<dc:creator>Gutiérrez Abejón, Eduardo</dc:creator>
<dc:creator>Herrera Gómez, Francisco Magno</dc:creator>
<dc:creator>Martín García, Débora</dc:creator>
<dc:creator>Tamayo Gómez, Eduardo</dc:creator>
<dc:creator>Álvarez González, Francisco Javier</dc:creator>
<dc:date>2021</dc:date>
<dc:description>Producción Científica</dc:description>
<dc:description>A high percentage of patients with COVID-19 (coronavirus disease 2019) have previous cardiovascular disease (CVD). The findings presented here came from an epidemiological population-based registry study (real-world data) that enrolled all in-hospital COVID-19 patients with previous CVD from 1 March to 31 May 2020. Death, other comorbidities, hospital stay variables, ventilation type, and main clinical outcomes were evaluated. In Castile and Leon, 35.83% of the 7307 in-hospital COVID-19 patients who participated in this study had previous CVD, particularly arrhythmias (48.97%), cerebrovascular disease (25.02%), ischemic heart disease (22.8%), and chronic heart failure (20.82%). Of the patients, 21.36% were men and more than 90% were over 65 years of age, and the mortality rate achieved 32.93%. The most used medicines were antibiotics (91.41%), antimalarials (73.3%), steroids (46.64%), and antivirals (43.16%). The main predictors of death were age over 65 years (OR: 5), ventilation needs (OR: 2.81), treatment with anti-SIRS (systemic inflammatory response syndrome) medicines (OR: 1.97), antivirals (OR: 1.74) or steroids (OR: 1.68), SIRS (OR: 5.75), SARS (severe acute respiratory syndrome) (OR: 2.44), or AKI (acute kidney injury) (OR: 1.63) occurrence. Chronic heart failure and cerebrovascular disease were associated with a worse clinical course of COVID-19, especially in men older than 65 years with diabetes who developed SIRS, SARS, or AKI.</dc:description>
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<dc:identifier>https://uvadoc.uva.es/handle/10324/59149</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>MDPI</dc:publisher>
<dc:subject>COVID-19 (Disease)</dc:subject>
<dc:subject>COVID-19</dc:subject>
<dc:subject>Cardiovascular system - Diseases - Treatment</dc:subject>
<dc:subject>Cerebrovascular disease</dc:subject>
<dc:subject>Cardiology</dc:subject>
<dc:subject>Heart failure</dc:subject>
<dc:subject>Mortality</dc:subject>
<dc:subject>2420 Virología</dc:subject>
<dc:subject>3207.04 Patología Cardiovascular</dc:subject>
<dc:title>A population-based registry analysis on hospitalized COVID-19 patients with previous cardiovascular disease: Clinical profile, treatment, and predictors of death</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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