2026-04-14T19:45:55Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/591492024-12-16T07:23:13Zcom_10324_1133com_10324_931com_10324_894col_10324_1209

A population-based registry analysis on hospitalized COVID-19 patients with previous cardiovascular disease: Clinical profile, treatment, and predictors of death Gutiérrez Abejón, Eduardo Herrera Gómez, Francisco Magno Martín García, Débora Tamayo Gómez, Eduardo Álvarez González, Francisco Javier COVID-19 (Disease) COVID-19 Cardiovascular system - Diseases - Treatment Cerebrovascular disease Cardiology Heart failure Mortality Producción Científica A high percentage of patients with COVID-19 (coronavirus disease 2019) have previous cardiovascular disease (CVD). The findings presented here came from an epidemiological population-based registry study (real-world data) that enrolled all in-hospital COVID-19 patients with previous CVD from 1 March to 31 May 2020. Death, other comorbidities, hospital stay variables, ventilation type, and main clinical outcomes were evaluated. In Castile and Leon, 35.83% of the 7307 in-hospital COVID-19 patients who participated in this study had previous CVD, particularly arrhythmias (48.97%), cerebrovascular disease (25.02%), ischemic heart disease (22.8%), and chronic heart failure (20.82%). Of the patients, 21.36% were men and more than 90% were over 65 years of age, and the mortality rate achieved 32.93%. The most used medicines were antibiotics (91.41%), antimalarials (73.3%), steroids (46.64%), and antivirals (43.16%). The main predictors of death were age over 65 years (OR: 5), ventilation needs (OR: 2.81), treatment with anti-SIRS (systemic inflammatory response syndrome) medicines (OR: 1.97), antivirals (OR: 1.74) or steroids (OR: 1.68), SIRS (OR: 5.75), SARS (severe acute respiratory syndrome) (OR: 2.44), or AKI (acute kidney injury) (OR: 1.63) occurrence. Chronic heart failure and cerebrovascular disease were associated with a worse clinical course of COVID-19, especially in men older than 65 years with diabetes who developed SIRS, SARS, or AKI. 2023-04-17T11:07:22Z 2023-04-17T11:07:22Z 2021 info:eu-repo/semantics/article Journal of Cardiovascular Development and Disease, 2021, Vol. 8, Nº. 12, 167 2308-3425 https://uvadoc.uva.es/handle/10324/59149 10.3390/jcdd8120167 167 12 Journal of Cardiovascular Development and Disease 8 2308-3425 eng https://www.mdpi.com/2308-3425/8/12/167 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ © 2021 The authors Atribución 4.0 Internacional MDPI SI