2026-05-05T09:19:41Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/592242026-04-09T10:28:20Zcom_10324_1179com_10324_931com_10324_894col_10324_1306

The influence of diet and probiotics on the response of solid tumours to immunotherapy: Present and future perspectives Olivares Hernández, Alejandro Figuero Pérez, Luis González Sarmiento, Rogelio León Jiménez, David Cruz Hernández, Juan Jesús Miramontes González, José Pablo Cancer Research Immunology Medicina Interna Oncología Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently on the survival rates associated with different neoplasms. The use of various antibiotics, probiotics, and prebiotics has been associated with changes in the gut microbiota, and this, in turn, with resistance to immunotherapy. Together with the above, a lower intake of red meat and greater consumption of a Mediterranean, vegetarian, or vegan diet have led to a new way of understanding the mechanisms of resistance to ICIs. Omega-3 and polyphenol supplements are also powerful regulators of the microbiome whose influence on the immune system. Therefore, this review covers the influence of diet and probiotics on the response to immunotherapy in patients who have solid tumours. 2023-04-20T07:43:54Z 2023-04-20T07:43:54Z 2023-04-20T07:43:54Z 2021 info:eu-repo/semantics/article Applied Sciences, 2021, vol. 11, n. 18, 8445 https://uvadoc.uva.es/handle/10324/59224 10.3390/app11188445 8445 18 Applied Sciences 11 2076-3417 eng https://www.mdpi.com/2076-3417/11/18/8445 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ © 2021 The Authors Atribución 4.0 Internacional MDPI