2026-04-27T21:25:26Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/594662024-12-16T07:16:20Zcom_10324_1133com_10324_931com_10324_894col_10324_1209

Impact of optimal timing of intake of multi-ingredient performance supplements on sports performance, muscular damage, and hormonal behavior across a ten-week training camp in elite cyclists: A randomized clinical trial Fernández Lázaro, Diego Mielgo Ayuso, Juan Francisco Valle Soto, Miguel del Adams, David P. Gutiérrez Abejón, Eduardo Seco Calvo, Jesús Nutrición Deporte Producción Científica Multi-ingredient performance supplements (MIPS), ingested pre- or post-workout, have been shown to increase physiological level effects and integrated metabolic response on exercise. The purpose of this study was to determine the efficacy of pre-and post-training supplementation with its own MIPS, associated with CHO (1 g·kg−1) plus protein (0.3 g·kg−1) on exercise-related benchmarks across a training camp for elite cyclists. Thirty elite male cyclists participated in a randomized non-placebo-controlled trial for ten weeks assigned to one of three groups (n = 10 each): a control group treated with CHO plus protein after training (CG); a group treated with MIPS before training and a CHO plus protein after training, (PRE-MIPS); a group treated with CHO plus protein plus MIPS after training, (POST-MIPS). Performance parameters included (VO2max, peak; median and minimum power (W) and fatigue index (%)); hormonal response (Cortisol; Testosterone; and Testosterone/Cortisol ratio); and muscle biomarkers (Creatine kinase (CK), Lactate dehydrogenase (LDH), and Myoglobin (Mb)) were assessed. MIPS administered before or after training (p ≤ 0.05) was significantly influential in attenuating CK, LDH, and MB; stimulating T response and modulating C; and improved on all markers of exercise performance. These responses were greater when MIPS was administered post-workout. 2023-05-03T09:15:47Z 2023-05-03T09:15:47Z 2021 info:eu-repo/semantics/article Nutrients, 2021, vol. 13, n. 11, 3746 https://uvadoc.uva.es/handle/10324/59466 10.3390/nu13113746 3746 11 Nutrients 13 2072-6643 eng https://www.mdpi.com/2072-6643/13/11/3746 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ © 2021 The Authors Atribución 4.0 Internacional MDPI SI