2026-04-27T14:34:07Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/62852021-06-23T09:48:37Zcom_10324_1133com_10324_931com_10324_894col_10324_1209

00925njm 22002777a 4500 dc Pérez Merino, Pablo author Parra Ruiz, Francisco Javier author Ibares Frías, Lucía author Gallego Muñoz, Patricia author Vázquez Lasa, Blanca author Benito Garzón, Lorena author San Román Calvar, José Alberto author Martínez García, María del Carmen author Merayo Lloves, Jesús author 2010 The objective of this work was to evaluate the potential use of less stiff materials based on acrylic copolymers of methyl methacrylate/2-ethylhexyl acrylate (MMA/EHA) as devices to correct, stabilize and improve the effect of poly(methyl methacrylate) (PMMA) intracorneal ring segments. MMA/EHA and PMMA intracorneal ring segments were surgically implanted in the corneas of Lohmann Classic hens. The effects of the intracorneal ring segments were assessed by optical measurements and corneal tolerance was evaluated through biomicroscopic examination over a 90-day observation period and by conventional histology. The experimental results demonstrated that the intracorneal ring segments made of MMA/EHA copolymers provided a significant change in the corneal curvature and an improved in vivo response compared to those obtained for PMMA rings, which was attributed to the higher flexibility of the copolymeric materials, indicating that these systems might be considered suitable as an alternative to those currently used, for application in clinical practice. Acta Biomaterialia, 2010, vol. 6, p. 2572-2579 1742-7061 http://uvadoc.uva.es/handle/10324/6285 10.1016/j.actbio.2010.01.014 2572 2579 Acta Biomaterialia 6 Cornea - Cirugía Clinical and pathological effects of different acrylic intracorneal ring segments in corneal additive surgery