2026-04-27T22:04:38Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/631842023-11-23T20:00:48Zcom_10324_40357com_10324_952com_10324_894col_10324_40358
Martínez Plaza, Elena
Ruiz Fortes, Pedro
Soto Negro, Roberto
Hernández Rodríguez, Carlos J.
Molina Martín, Ainhoa
Arias Puente, Alfonso
Piñero, David P.
2023-11-23T09:31:53Z
2023-11-23T09:31:53Z
2022
Diagnostics, 2022, Vol. 12, Nº. 5, 1167
2075-4418
https://uvadoc.uva.es/handle/10324/63184
10.3390/diagnostics12051167
1167
5
Diagnostics
12
2075-4418
Producción Científica
This study enrolled 61 volunteers (102 eyes) classified into subjects < 50 years (group 1) and subjects ≥ 50 years (group 2). Dysfunctional Lens Index (DLI); opacity grade; pupil diameter; and corneal, internal, and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Mean DLI was 8.89 ± 2.00 and 6.71 ± 2.97 in groups 1 and 2, respectively, being significantly higher in group 1 in all and right eyes (both p < 0.001). DLI correlated significantly with age (Rho = −0.41, p < 0.001) and pupil diameter (Rho = 0.20, p = 0.043) for all eyes, and numerous internal and ocular root-mean square HOAs for right, left, and all eyes (Rho ≤ −0.25, p ≤ 0.001). Mean opacity grade was 1.21 ± 0.63 and 1.48 ± 1.15 in groups 1 and 2, respectively, with no significant differences between groups (p ≥ 0.29). Opacity grade significantly correlated with pupil diameter for right and all eyes (Rho ≤ 0.33, p ≤ 0.013), and with some ocular root-mean square HOAs for right and all eyes (Rho ≥ 0.23, p ≤ 0.020). DLI correlates with age and might be used complementary to other diagnostic measurements for assessing the dysfunctional lens syndrome. Both DLI and opacity grade maintain a relationship with pupil diameter and internal and ocular HOAs, supporting that the algorithms used by the device may be based, in part, on these parameters.
Ministerio de Economía, Industria y Competitividad y Unión Europea - (RYC-2016-20471)
application/pdf
eng
MDPI
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
© 2022 The Authors
Atribución 4.0 Internacional
Eye - Diseases
Ojo - Enfermedades y defectos
Crystalline lens
Cristalino - Enfermedades
Cataract
Cataratas (Oftalmología)
Higher-order aberrations
Ophthalmology
Clinical biochemistry
Bioquímica clínica
Medical technology
Dysfunctional lens syndrome
Síndrome del cristalino disfuncional
32 Ciencias Médicas
3201.09 Oftalmología
3314 Tecnología Médica
Characterization of dysfunctional lens index and opacity grade in a healthy population
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
https://www.mdpi.com/2075-4418/12/5/1167
SI