2026-05-05T18:29:14Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/631842023-11-23T20:00:48Zcom_10324_40357com_10324_952com_10324_894col_10324_40358

00925njm 22002777a 4500 dc Martínez Plaza, Elena author Ruiz Fortes, Pedro author Soto Negro, Roberto author Hernández Rodríguez, Carlos J. author Molina Martín, Ainhoa author Arias Puente, Alfonso author Piñero, David P. author 2022 This study enrolled 61 volunteers (102 eyes) classified into subjects < 50 years (group 1) and subjects ≥ 50 years (group 2). Dysfunctional Lens Index (DLI); opacity grade; pupil diameter; and corneal, internal, and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Mean DLI was 8.89 ± 2.00 and 6.71 ± 2.97 in groups 1 and 2, respectively, being significantly higher in group 1 in all and right eyes (both p < 0.001). DLI correlated significantly with age (Rho = −0.41, p < 0.001) and pupil diameter (Rho = 0.20, p = 0.043) for all eyes, and numerous internal and ocular root-mean square HOAs for right, left, and all eyes (Rho ≤ −0.25, p ≤ 0.001). Mean opacity grade was 1.21 ± 0.63 and 1.48 ± 1.15 in groups 1 and 2, respectively, with no significant differences between groups (p ≥ 0.29). Opacity grade significantly correlated with pupil diameter for right and all eyes (Rho ≤ 0.33, p ≤ 0.013), and with some ocular root-mean square HOAs for right and all eyes (Rho ≥ 0.23, p ≤ 0.020). DLI correlates with age and might be used complementary to other diagnostic measurements for assessing the dysfunctional lens syndrome. Both DLI and opacity grade maintain a relationship with pupil diameter and internal and ocular HOAs, supporting that the algorithms used by the device may be based, in part, on these parameters. Diagnostics, 2022, Vol. 12, Nº. 5, 1167 2075-4418 https://uvadoc.uva.es/handle/10324/63184 10.3390/diagnostics12051167 1167 5 Diagnostics 12 2075-4418 Eye - Diseases Ojo - Enfermedades y defectos Crystalline lens Cristalino - Enfermedades Cataract Cataratas (Oftalmología) Higher-order aberrations Ophthalmology Clinical biochemistry Bioquímica clínica Medical technology Characterization of dysfunctional lens index and opacity grade in a healthy population