2026-05-05T13:23:04Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/637352024-12-13T12:33:27Zcom_10324_1133com_10324_931com_10324_894col_10324_1209

00925njm 22002777a 4500 dc Fernández Lázaro, Diego author Sánchez Serrano, Nerea author Rabail, Roshina author Aadil, Rana Muhammad author Mielgo Ayuso, Juan Francisco author Radesca Fabiano, Krizia author Garrosa, Evelina author 2023 Supplementation with probiotics in sports is on the rise with the aim of improving health and athletic performance. Since intense exercise-induced muscle damage leads to an inflammatory process by increasing circulating inflammatory cytokines, probiotic supplementation may modulate and correct the inflammation. We systematically reviewed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in the Scopus, Web of Science, and Medline databases for the 10 years until January 2023. This review aimed to evaluate probiotic supplementation as a strategy for modulating inflammation in healthy physically active adults or athletes. Studies were indexed to assess the effect of probiotic supplementation on cytokine behavior in the inflammatory response in physically active individuals. Of the 136 studies identified in the search, 13 met the inclusion criteria, and their quality was assessed using the McMaster Critical Review Form. The results of these trials indicated a significant improvement in inflammatory cytokines in probiotic-supplemented participants, with a significant increase in anti-inflammatory cytokines (IL-10) and a significant decrease in proinflammatory cytokines (IL-6, TNF-α, and IL-8). This would create uncertainty about probiotics’ effect on interleukins’ behavior after exercise, and further clinical trials are needed to establish a solid basis. Applied Sciences, 2023, Vol. 13, Nº. 6, 3448 2076-3417 https://uvadoc.uva.es/handle/10324/63735 10.3390/app13063448 3448 6 Applied Sciences 13 2076-3417 Athletes - Nutrition Deportistas - Alimentación Dietary supplements Supplementation Probiotics Probióticos Exercise Physical activity Ejercicio fisico Cytokines Inflammation Inflamación Meta-analysis Sports medicine Medicina deportiva Dietetics Dietética Is probiotics supplementation an appropriate strategy to modulate inflammation in physically active healthy adults or athletes? A systematic review