2026-04-22T22:17:40Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/654572025-02-06T10:57:27Zcom_10324_1166com_10324_931com_10324_894col_10324_1338

Sánchez Hernández, Eva Álvarez Martínez, Javier González García, Vicente Casanova Gascón, José Martín Gil, Jesús Martín Ramos, Pablo 2024-01-31T15:10:53Z 2024-01-31T15:10:53Z 2023 Molecules, Agosto 2023, 28, 15, 5861 1420-3049 https://uvadoc.uva.es/handle/10324/65457 10.3390/molecules28155861 5861 15 Molecules 28 1420-3049 Producción Científica Helichrysum stoechas is a singular halophyte that has been shown to have anti-inflammatory, antioxidant, and allelopathic properties. In the work presented herein, we have characterized its inflorescences hydromethanolic extract and assessed its antifungal activity for the pre- and postharvest management of tomato crop diseases. Gas chromatography–mass spectrometry characterization of the extract showed that 4-ethenyl-1,3-benzenediol, 2,3-dihydro-benzofuran, quinic acid, 3,5-dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-1-benzopyran-4-one, 1,6-anhydro-β-D-glucopyranose, catechol, scopoletin, and maltol were the main constituents. The co-occurrence of pyranones, benzenediols, and quinic acids as phytoconstituents of H. stoechas extract resulted in promising in vitro minimum inhibitory concentrations of 500, 375, 500, 187.5, 187.5, and 375 μg·mL−1 against mycelia of Alternaria alternata, Colletotrichum coccodes, Fusarium oxysporum f. sp. lycopersici, Rhizoctonia solani, Sclerotinia sclerotiorum, and Verticillium dahliae, respectively. Further, to assess the potential of H. stoechas inflorescence extract for postharvest tomato crop protection, ex situ tests were conducted against C. coccodes, obtaining high protection at a dose of 750 μg·mL−1. Taking into consideration that the demonstrated activity is among the highest reported to date for plant extracts and comparable to that of the synthetic fungicides tested as positive controls, H. stoechas inflorescence extract may be put forward as a promising biorational and may deserve further testing in field-scale studies Agencia Estatal de Investigación PID2020-116055RB-C22 Gobierno de Aragón A11-20R application/pdf spa MDPI info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ Attribution-NonCommercial-NoDerivatives 4.0 Internacional Helichrysum stoechas (L.) Moench Inflorescence Extract for Tomato Disease Management info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion SI