2026-05-05T19:48:26Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/674322024-10-29T11:53:14Zcom_10324_1134com_10324_931com_10324_894col_10324_1213

Iglesias Álvarez, María del Rosario Citores González, Lucía Gay, Claudia C. Ferreras Rodríguez, José Miguel 2024 Producción Científica The control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly. Plants are an excellent source for this purpose because they have developed defense mechanisms to cope with fungal infections. Among the plant proteins that play a role in defense are ribosome-inactivating proteins (RIPs), enzymes obtained mainly from angiosperms that, in addition to inactivating ribosomes, have been studied as antiviral, fungicidal, and insecticidal proteins. In this review, we summarize and discuss the potential use of RIPs (and other proteins with similar activity) as antifungal agents, with special emphasis on RIP/fungus specificity, possible mechanisms of antifungal action, and the use of RIP genes to obtain fungus-resistant transgenic plants. It also highlights the fact that these proteins also have antiviral and insecticidal activity, which makes them very versatile tools for crop protection. application/pdf https://uvadoc.uva.es/handle/10324/67432 eng MDPI Antifungal protein Adenine polynucleotide glycosylase Fungus-resistant transgenic plants Plant pathogenic fungi Ribosome-inactivating protein (RIP) rRNA glycosylase 3214 Toxicología 2302.27 Proteínas 2301 Química Analítica 2302 Bioquímica Antifungal activity of ribosome-inactivating proteins info:eu-repo/semantics/article TEXT UVaDOC. Repositorio Documental de la Universidad de Valladolid Hispana