2026-05-05T18:23:36Zhttps://uvadoc.uva.es/oai/request
oai:uvadoc.uva.es:10324/709812025-02-10T13:12:39Zcom_10324_1179com_10324_931com_10324_894col_10324_1306
UVaDOC author Briongos Figuero, Laisa Socorro author Bachiller Luque, Pablo author Palacios Martín, T. author González Sagrado, Manuel author Eiros Bouza, José María 2024-10-28T12:35:06Z 2024-10-28T12:35:06Z 2011 Int J Clin Pract. 2012 Sep;66(9):891-6 1464-2662 https://uvadoc.uva.es/handle/10324/70981 10.1111/j.1468-1293.2010.00844.x 22 1 30 HIV Medicine 12 Objectives: Health-related quality of life (HRQL) is used in the assessment of chronic illness. Regarding HIV infection, HRQL assessment is an objective for physicians and institutions since antiretroviral treatment delays HIV clinical progression. The aim of this study was to determine the factors with the most influence on HRQL in HIV-infected people and to create a predictive model. Methods: We conducted a cross-sectional study in 150 patients in a tertiary hospital. HRQL data were collected using the Medical Outcomes Study HIV Health Survey (MOS-HIV) questionnaire. The research team created a specific template with which to gather clinical and sociodemographic data. Adherence was assessed using the Simplified Medication Adherence Questionnaire (SMAQ) and depression data were obtained using the Beck Depression Inventory, Second Edition (BDI-II) inventory. Logistic regression models were used to identify determinants of HRQL. Results: HIV-related symptoms and presence of depression were found to be negatively associated with all the MOS-HIV domains, the Physical Health summary score and the Mental Health summary score. Patients receiving protease inhibitor (PI)-based treatment had lower scores in four of the 11 domains of the MOS-HIV questionnaire. Gender, hospitalization in the year before enrolment, depression and parenthood were independently related to the Physical Health Score; depression and hepatitis C virus coinfection were related to the Mental Health Score. Conclusions: Optimization of HRQL is particularly important now that HIV infection can be considered a chronic disease with the prospect of long-term survival. Quality of life should be monitored in follow-up of HIV-infected patients. The assessment of HRQL in this population can help us to detect problems that may influence the progression of the disease. This investigation highlights the importance of a multidisciplinary approach to HIV infection. eng Assessment of factors influencing health-related quality of life in HIV-infected patients info:eu-repo/semantics/article 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URL https://uvadoc.uva.es/bitstream/10324/70981/2/Assessment%20of%20factors%20influencing%20HRQoL%20in%20HIV-infected%20patients.%20HIV%20medicine%202010%20DOI.pdf File MD5 ee2285d577ad336dfe97f41a70f43a93 128932 application/pdf Assessment of factors influencing HRQoL in HIV-infected patients. HIV medicine 2010 DOI.pdf