2026-04-27T19:53:11Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/728502025-01-13T11:05:49Zcom_10324_1138com_10324_931com_10324_894col_10324_1226

Simón Pérez, Clarisa Martín Ferrero, Miguel Ángel Hernández Cortés, Pedro Coco Martín, María Begoña Rosales, Roberto S. 2024-12-19T07:34:09Z 2024-12-19T07:34:09Z 2024 Archives of Orthopaedic and Trauma Surgery, septiembre 2024, vol. 144, p. 4275–4282 https://uvadoc.uva.es/handle/10324/72850 10.1007/s00402-024-05525-w 4275 9 4282 Archives of Orthopaedic and Trauma Surgery 144 1434-3916 Aims: To assess the survival function of cementless total trapezium metacarpal prostheses (TTMPs) at 20 years, to compare survival functions by trapezium size, and to evaluate the association between the instantaneous risk of TTMP failure and small trapezium size using a multivariate Cox regression model. Methods: This observational cohort study included 221 consecutive patients with a mean follow-up after TTMP of 138.1 months (maximum of 246 months). Kaplan-Meier and actuarial life-table methods were used to evaluate the survival function of the cohort. Kaplan-Meier survival curves were compared by trapezium size. Multivariate Cox regression analysis was used to determine the effect of potential confounders on the association between small trapezium and the instantaneous risk of TTMP failure. Results: At the end of follow-up, there was a 89.01% chance of the TTMP surviving for 246 months or more. There was an association between TTMP survival time and trapezium size showing a significant trend such that the survival curves were significantly higher with larger trapezium size (Mantel-Cox test, p = 0.0001; Wilcoxon- Breslow test, p = 0.0002; Tarone-Ware test, p = 0.0001).The unadjusted Cox regression model showed a significant association between small trapezium size (smaller than 9 mm) and the instantaneous risk of TTPM failure (HR: 7.37, 95% CI: 2.46-22.07). In the multivariate Cox analysis, "age", "trapezium morphology", and "complications" were confounders in the association between small trapezium size and the hazard ratio of prosthetic failure (HR = 3.76; 95% CI 0.96 to 13.82). Conclusions: These results confirm the long-term functional survival of TTMP prostheses and reveal a significant increase in trend of the survival curve with larger trapezium size. Patient age, trapezium morphology, and the presence of post-surgical complications are confounders in the association between small trapezium size and the hazard ratio of TTMP failure. spa info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ Atribución 4.0 Internacional Assocation between trapezium size and failure of total trapeziometacarpal prosthesis. A survival analysis info:eu-repo/semantics/article