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oai:uvadoc.uva.es:10324/729582025-09-09T10:02:57Zcom_10324_1185com_10324_931com_10324_894col_10324_1346

Martín Gómez, Beatriz Valverde Bastardo, Silvia Bernal del Nozal, José Ares Sacristán, Ana María 2024-12-20T12:35:09Z 2024-12-20T12:35:09Z 2024 Food Chemistry, junio 2024, vol. 450, 139358 0308-8146 https://uvadoc.uva.es/handle/10324/72958 10.1016/j.foodchem.2024.139358 139358 Food Chemistry 450 A new analytical methodology was proposed to determine fourteen bisphenols in honeys from different botanical origins using ultra-high performance liquid chromatography-tandem mass spectrometry. A fast, efficient, environmentally-friendly and simple sample treatment (recoveries between 81% and 116%; matrix effect <20% for all studied compounds except for bisphenol E, F and S) was proposed, which involved a solvent microextraction with acetone and a small volume/amount of 1-hexanol. Chromatographic analysis (< 15 min) was performed in a Kinetex EVO C18 column under gradient elution mode. The method was validated in terms of selectivity, limits of detection (0.2–1.5 μg/kg) and quantification (0.5–4.7 μg/kg), linearity, matrix effect, trueness, and precision (relative standard deviation <17%). Finally, thirty honey samples were analyzed, revealing the presence of residues of nine bisphenols in some of them. However, quantification was possible only in two cases for bisphenol A, with a concentration of approximately 13 μg/kg. eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ © 2024 The Authors Attribution-NonCommercial-NoDerivatives 4.0 Internacional Development and validation of an analytical methodology based on solvent microextraction and UHPLC-MS/MS for determining bisphenols in honeys from different botanical origins info:eu-repo/semantics/article