2026-04-23T00:17:04Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/732682025-01-13T08:17:10Zcom_10324_966com_10324_952com_10324_894col_10324_967

Cisnal De La Rica, Ana Alonso Linaje, Gonzalo Fraile Marinero, Juan Carlos Pérez Turiel, Javier Álvarez, Pablo Martinez, Socorro 2025-01-09T09:25:15Z 2025-01-09T09:25:15Z 2024 Journal of Clinical Medicine, 2024, vol. 13, n. 6, p. 1543 https://uvadoc.uva.es/handle/10324/73268 10.3390/jcm13061543 1543 6 Journal of Clinical Medicine 13 2077-0383 Prolonged hospitalization in severe COVID-19 cases can lead to substantial muscle loss and functional deterioration. While rehabilitation is essential, conventional approaches face capacity challenges. Therefore, evaluating the effectiveness of robotic-assisted rehabilitation for patients with post-COVID-19 fatigue syndrome to enhance both motor function and overall recovery holds paramount significance. Our objective is to assess the effectiveness of rehabilitation in post-COVID-19 patients with upper extremity impairment through the utilization of a hand exoskeleton-based robotic system. Methods: A total of 13 participants experiencing acute or limited functional or strength impairment in an upper extremity due to COVID-19 were enrolled in the study. A structured intervention consisted of 45 min therapy sessions, conducted four times per week over a six-week period, utilizing a hand exoskeleton. The research employed standardized health assessments, motion analysis, and semi-structured interviews for pre-intervention and follow-up evaluations. Paired sample t-tests were employed to statistically analyze the outcomes. Results: The outcomes showed a reduction in overall dependence levels across participants, positive changes in various quality of life-related measurements, and an average increase of 60.4 ± 25.7% and 28.7 ± 11.2% for passive and active flexion, respectively. Conclusions: Our data suggest that hand exoskeleton-based robotic systems hold promise to optimize the rehabilitation outcomes following severe COVID-19. Trial registration: ID NCT06137716 at ClinicalTrials.gov. Este trabajo ha sido financiado por el Instituto para la Competitividad Empresarial de Castilla y León (España) en el marco de los proyectos de I+D 2021 en el contexto del brote COVID-19 y cofinanciado por fondos europeos FEDER en el marco del objetivo temático 1, que pretende promover el desarrollo tecnológico, la innovación y la investigación de alta calidad. application/pdf spa MDPI info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ Attribution-NonCommercial-NoDerivatives 4.0 Internacional case report COVID-19 musculoskeletal sequalae physical rehabilitation robotic therapy Tackling Post-COVID-19 Rehabilitation Challenges: A Pilot Clinical Trial Investigating the Role of Robotic-Assisted Hand Rehabilitation info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.mdpi.com/2077-0383/13/6/1543 SI