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Rodríguez Cabello, José Carlos González de Torre, Israel Santos García, María Mercedes Testera Gorgojo, Ana María Alonso Rodrigo, Matilde 2025-02-05T14:29:22Z 2025-02-05T14:29:22Z 2016 Neves, Nuno M. y Reis, Rui L. (eds.). Biomaterials from nature for advanced devices and therapies. Hoboken (New Jersey): John Wiley & Sons, 2016, p. 444-474 9781118478059 https://uvadoc.uva.es/handle/10324/74850 10.1002/9781119126218.ch24 444 474 Biomaterials from nature for advanced devices and therapies Producción Científica Protein modification is an area of an intense research and many methods have been developed with applications in fields including biology, chemistry and medicine, as they are powerful tools for studying protein expression and localization, and engineering the functions of protein both in vitro and in live cells or in vivo to create new biocatalysts and bioanalytical tools. There are different high precision protein modification methods which can be roughly divided into two categories. The first involve the use of a genetic modification system and the second is based on the labeling of expressed proteins taking advantages of the chemical reactivity of the amino acid side chains. As they occur after the protein biosynthesis step, these chemical modifications, are commonly referred to as post-translational modifications (PTMs). Natural polysaccharides and their derivatives are emerging polymers in pharmaceutical and biomedical fields such as tissue engineering, particularly for cartilage, drug delivery devices and gel-entrapment systems for cells immobilization. application/pdf eng Wiley info:eu-repo/semantics/restrictedAccess https://creativecommons.org/licenses/by-nc-nd/4.0/ © 2016 John Wiley & Sons, Inc Atribución-NoComercial-SinDerivados 4.0 Internacional Chemical modification of biomaterials from nature info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion https://onlinelibrary.wiley.com/doi/10.1002/9781119126218.ch24 23 Química 32 Ciencias Médicas