2026-05-05T18:31:24Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/789062026-03-17T11:15:55Zcom_10324_35294com_10324_952com_10324_894col_10324_35295

Cruz, Pedro Lebrero Fernández, Raquel Vergara Fernández, Alberto Muñoz Torre, Raúl 2025-10-22T12:25:57Z 2025-10-22T12:25:57Z 2025 Chemical Engineering Journal, 2025, vol. 522, p. 167871 1385-8947 https://uvadoc.uva.es/handle/10324/78906 10.1016/j.cej.2025.167871 167871 Chemical Engineering Journal 522 Producción Científica The microbial valorization of CO2 requires the development of novel bioreactor configurations capable of ensuring a cost-effective gas-liquid mass transfer. This study presents the design, characterization and performance evaluation of a novel Airlift Taylor Flow Reactor (ATFR), which integrates the gas-induced liquid recirculation of airlift systems, with the high gas-liquid mass transfer potential of Taylor flow in multicapillary systems. The liquid recirculation flow in the downcomer was quantified using a colour tracer method, and the volumetric oxygen mass transfer coefficient (kLa) was determined via the sulphite oxidation method, both with and without forced recirculation. The results showed that the implementation of forced mechanical recirculation via a centrifugal pump negatively impacted the total liquid recirculation and kLa. A maximum kLa of 891 ± 23 h 1 was achieved at a gas flow rate of 60 L min 1, representing a 75 % increase compared to the same condition with external forced liquid recirculation. The autotrophic growth of Cupriavidus necator showed a direct correlation with kLa, with a 171 % increase in maximum cell concentration and a 67 % increase in the specific growth rate when kLa increased from 183 to 364 h 1. These findings highlight the potential of the ATFR as a promising platform for gas-liquid mass transfer-limited processes, particularly in systems bioconverting poorly soluble gases such as H2, CH4, CO and O2. Ministerio de Ciencia e Innovación (MCIN) / Agencia Estatal de Investigación (AEI): PDC2022-133394-I00 (MCIN/AEI/10.13039/501100011033/UE/PRTR) Agencia Nacional de Investigación y Desarrollo (ANID) de Chile a través de los siguientes proyectos: Beca Nacional de Doctorado Folio 21220445, Cotutela Doctoral Folio 21220445, Anillo ATE220045 y Fondecyt 1240411 application/pdf eng Elsevier info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ © 2025 The Author(s) Atribución 4.0 Internacional Bioreactors Reactor (ATFR) 23 Química Airlift Taylor Flow bioreactors as a novel platform to enhance H2-assisted CO2 bioconversion processes info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://www.sciencedirect.com/science/article/pii/S138589472508711X SI