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<dc:creator>Sánchez Hernández, Eva</dc:creator>
<dc:creator>Clérigo de Santiago, Jorge</dc:creator>
<dc:creator>González García, Vicente</dc:creator>
<dc:creator>Herrera Sánchez, Marta</dc:creator>
<dc:creator>Marcos Robles, José Luis</dc:creator>
<dc:creator>Martín Gil, Jesús</dc:creator>
<dc:creator>Martín Ramos, Pablo</dc:creator>
<dc:date>2026</dc:date>
<dc:description>Producción Científica</dc:description>
<dc:description>The coffee industry generates a large amount of waste that is usually discarded, creating an environmental and&#xd;
economic problem. However, these by-products can be a valuable source of bioactive compounds with antimi-&#xd;
crobial properties and present an opportunity for use in crop protection, either pre- or post-harvest. Following&#xd;
the principles of the circular economy, this study proposes the extraction and characterization of bioactive&#xd;
products from coffee by-products, as well as the evaluation of their antifungal activity against pathogens that&#xd;
affect coffee plants and/or stored coffee beans, such as Fusarium xylarioides, Aspergillus flavus, A. niger, and&#xd;
Penicillium verrucosum. In vitro activity assays demonstrate high antimicrobial activity of the husk, parchment,&#xd;
defective green beans with silverskin, and silverskin extracts, with minimum inhibitory concentrations ranging&#xd;
from 15.6 to 375 μg mL 1 against F. xylarioides, 31.2–1000 μg mL 1 against A. flavus, 62.5–1000 μg mL 1 against&#xd;
A. niger, and 62.5–1500 μg mL 1 against P. verrucosum, depending on the by-product extract used. The most&#xd;
effective extract, derived from silverskin, was evaluated for pre-harvest protection of coffee plants and&#xd;
demonstrated complete inhibition of F. xylarioides-induced tracheomycosis at 15.6 μg mL 1. In turn, a concen-&#xd;
tration of 62.5 μg mL 1 of the silverskin extract was sufficient to prevent fungal growth of A. flavus, A. niger, and&#xd;
P. verrucosum on coffee beans. This concentration also prevented mycotoxin production by A. flavus, while a&#xd;
higher concentration of 125 μg mL 1 was required to prevent aflatoxin production by A. niger. The reported&#xd;
findings support coffee by-products extracts as promising alternatives to synthetic fungicides, with the potential&#xd;
to improve the sustainability of the coffee industry.</dc:description>
<dc:format>application/pdf</dc:format>
<dc:identifier>https://uvadoc.uva.es/handle/10324/80103</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>Elsevier</dc:publisher>
<dc:subject>31 Ciencias Agrarias</dc:subject>
<dc:title>Circular economy approach to coffee processing residue valorization: Bioactive by-product extracts for managing pre- and post-harvest fungal pathogens</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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