2026-04-27T12:21:51Zhttps://uvadoc.uva.es/oai/request
oai:uvadoc.uva.es:10324/809442026-01-08T10:37:45Zcom_10324_1138com_10324_931com_10324_894col_10324_1226
UVaDOC author Varga Martínez, Olga de la author Navarro Pérez, R. author López Herrero, Rocío author Montesinos Fadrique, S. author Almoguera Fernández, J. author Alonso Fernández, M. author Artiaga Candia, M. author Becerra Bolaños, A. author Bugueño, N. author Casasempere Sanus, A. author Contreras López, L. author Cuadrillero Sánchez, R. author De la Rosa Estadella, M. author de la Torre Riveiro, I. author del Val Peciña, E. author Delgado Martí, C. author Edo Cebollada, L. author Fernández Fernández, R. author Fernández Rodríguez, J. author Ferrer Gómez, C. author Giné Servén, M. author González Pereira, A. author Guereca Gala, A. author Herrera Soto, A. author Illodo Miramontes, G. author Infantes Morales, M.E. author Marcos Vidal, J.M. author Martínez López, A. author Martínez Ruiz, A. author Martínez Rafael, Beatriz author Matute González, A. author Pariente Juste, L. author Poves Álvarez, Rodrigo author Regueira Fernández, Álvaro author Renedo Fernández, A. author Rodríguez Álvarez, A.A. author Rodríguez Calvo, A. author Rodríguez Conesa, MA author Sánchez González, C. author Tobar Gonzalo, C. author Varela Rodríguez, L. author Veloso de Sousa, R. author Muñoz Moreno, M.F. author Escudero Gómez, G. author Tamayo Gómez, Eduardo author Varela Duran, M. author Badenes Quiles, R. 2025-12-22T10:12:26Z 2025-12-22T10:12:26Z 2025 Journal of Clinical Anesthesia, 2025, vol. 107, p. 112018 0952-8180 https://uvadoc.uva.es/handle/10324/80944 10.1016/j.jclinane.2025.112018 112018 Journal of Clinical Anesthesia 107 Background: Postoperative delirium increases morbidity, mortality, hospital stays, and costs, though 30–40 % of cases are preventable. This study assessed early delirium incidence in 2442 surgical patients across 43 Spanish hospitals, analyzing it by surgery type and related factors. Conducted from November 14 and 21, 2023, with follow-ups on days 2 and 60, it provides insights into factors influencing postoperative delirium and outcomes. Methods: The study included three phases: (1) recruitment and assessment of surgical patients on November 14 and 21, 2023, across all centers; (2) monitoring for delirium by postoperative day 2; and (3) a follow-up at 60 days. Delirium was diagnosed using the CAM, CAM-ICU, and 4AT scales. The sample size was estimated and multivariable logistic regression and Cox regression analysis were performed to identify independent risk factors and assess the impact of delirium on mortality. Results: A total of 2442 surgical patients were recruited, mainly male (51.9 %), with a mean age of 76 ± 16 years. The delirium incidence was 3.93 %, with four preoperative independent risk factors identified through multi- variate analysis.: Patient age (odds ratio (OR) 1.05, 95 % CI 1.04 to 1.08, p > 0.001), cognitive impairment (SBT > 6 points) (OR 1.12, 95 % CI 1.08 to 1.15, p < 0.001), substance use disorder (SUD) (OR 3.97, 95 % CI 1.05 to 14.93, p = 0.042) and alcoholism (OR 1.92, 95 % CI 1.20 to 3.07, p = 0.006), with a model AUROC of 0.81 (95 % CI 0.76 to 0.85). Postoperative delirium was associated with longer hospital stays and significantly higher mortality at 60 days (8.3 % vs 0.6 %). Conclusion: This Spanish study found that postoperative delirium, linked to longer hospital stays and higher mortality, requires early detection and prevention to improve outcomes. eng Atribución 4.0 Internacional Incidence and risk factors of postoperative delirium after surgery in the spanish population: The DELPO study info:eu-repo/semantics/article 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URL https://uvadoc.uva.es/bitstream/10324/80944/1/Incidence-risk-factors-postoperative.pdf File MD5 25e762ffd56927bf4aa01ffc38225168 1658598 application/pdf Incidence-risk-factors-postoperative.pdf