2026-04-22T21:09:33Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/84192024-12-18T10:32:41Zcom_10324_1131com_10324_931com_10324_894col_10324_1201

Carreño, E. Saornil Álvarez, María Antonia García Álvarez, Ciro López-Lara Martín, Francisco Frutos Baraja, Jesús María De Almaraz Gómez, Ana 2015-02-19T09:33:22Z 2015-02-19T09:33:22Z 2012 Eye . 2012 Jan;26(1):159-156 0950-222X http://uvadoc.uva.es/handle/10324/8419 10.1038/eye.2011.257 159 1 156 Eye 26 Producción Científica The aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population. METHODS: Retrospective review of the medical records of patients with ODM among patients with UM. RESULTS: Ten (11 eyes) of 400 patients (2.7%) with UM associated had ODM. The mean age at diagnosis of UM among patients with ODM was 62 years. One patient had bilateral tumours. UM was diagnosed during a routine-examination in two cases. All tumours were medium (7/11) or large (4/11) in size, with a mean maximum base of 13 mm and height of 7 mm. No patient had extraocular extension or metastatic disease at diagnosis. Enucleation was done in five cases and I-125-brachytherapy in six. The mean follow-up was 43 months. One patient died because of metastasis 2 years after enucleation; one patient is currently on treatment of systemic metastasis 11 years after. CONCLUSIONS: ODM is more frequent in spanish population with UM than in American population. Despite the risk of UM in ODM, it is often diagnosed late when a conservative treatment is not indicated. application/pdf eng Nature Publishing Group info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ Attribution-NonCommercial-NoDerivatives 4.0 International Melanoma ocular Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma info:eu-repo/semantics/article SI