2026-04-14T19:24:15Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/84192024-12-18T10:32:41Zcom_10324_1131com_10324_931com_10324_894col_10324_1201

Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma Carreño, E. Saornil Álvarez, María Antonia García Álvarez, Ciro López-Lara Martín, Francisco Frutos Baraja, Jesús María De Almaraz Gómez, Ana Melanoma ocular Producción Científica The aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population. METHODS: Retrospective review of the medical records of patients with ODM among patients with UM. RESULTS: Ten (11 eyes) of 400 patients (2.7%) with UM associated had ODM. The mean age at diagnosis of UM among patients with ODM was 62 years. One patient had bilateral tumours. UM was diagnosed during a routine-examination in two cases. All tumours were medium (7/11) or large (4/11) in size, with a mean maximum base of 13 mm and height of 7 mm. No patient had extraocular extension or metastatic disease at diagnosis. Enucleation was done in five cases and I-125-brachytherapy in six. The mean follow-up was 43 months. One patient died because of metastasis 2 years after enucleation; one patient is currently on treatment of systemic metastasis 11 years after. CONCLUSIONS: ODM is more frequent in spanish population with UM than in American population. Despite the risk of UM in ODM, it is often diagnosed late when a conservative treatment is not indicated. 2015-02-19T09:33:22Z 2015-02-19T09:33:22Z 2012 info:eu-repo/semantics/article Eye . 2012 Jan;26(1):159-156 0950-222X http://uvadoc.uva.es/handle/10324/8419 10.1038/eye.2011.257 159 1 156 Eye 26 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ Attribution-NonCommercial-NoDerivatives 4.0 International Nature Publishing Group SI