2026-04-30T00:42:39Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/842482026-04-21T19:21:38Zcom_10324_1186com_10324_931com_10324_894col_10324_1404
UVaDOC
author
Ferraro, Valentina
author
Sole, Roberto
author
Álvarez Miguel, Lucía
2026-04-21T15:21:15Z
2026-04-21T15:21:15Z
2023
Appl Organomet Chem. 2023;37:e7182.
0268-2605
https://uvadoc.uva.es/handle/10324/84248
10.1002/aoc.7182
e7182
8
Applied Organometallic Chemistry
37
1099-0739
Three neutral Cu(I) complexes bearing 2,6-dimethylphenyl isocyanide (CNXyl) and different triatomic pseudohalogens (SCN−, OCN− and N3−) as ligands were efficiently synthesized and characterized. The solid-state structures were unambiguously determined through single-crystal X-ray diffraction, revealing unexpected bridging coordination modes in the case of OCN− and N3−. All the complexes were tested for azide-alkyne cycloaddition (CuAAC), showing interesting catalytic activity towards the formation of 1,4-disubstituted-1,2,3-triazoles for the cyanato and the azido Cu(I) complexes. Both species afforded yields above 90% with 0.5 mol% of catalyst at 50°C for 24 h. Several alkynes and azides were tested using the more active azido Cu(I) complex, affording the corresponding triazoles in high yields. The azido Cu(I) complex also induced the intramolecular CuAAC in the presence of dimethyl acetylenedicarboxylate and benzyl bromide/phenylacetylene.
eng
Isocyanide Cu(I) complexes with unexpected μ2‐bridging pseudohalides: Synthesis, characterization and catalytic activity towards CuAAC
info:eu-repo/semantics/article
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https://uvadoc.uva.es/bitstream/10324/84248/1/Applied%20Organom%20Chemis%20-%202023%20-%20Ferraro.pdf
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Applied Organom Chemis - 2023 - Ferraro.pdf