2024-03-28T18:43:21Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/409902023-03-17T11:36:56Zcom_10324_22821com_10324_954com_10324_894col_10324_22822
Jiménez López, María del Pilar
Tejero del Río, Jesús
Córdoba Diaz, Damián
Quinto Fernández, Emiliano José
Garrosa García, Manuel
Gayoso Rodríguez, Manuel José
Girbés Juan, Tomás
2020-06-04T11:17:27Z
2020-06-04T11:17:27Z
2015
Toxins, 2015, vol. 7, n. 3. p. 648-658
2072-6651
http://uvadoc.uva.es/handle/10324/40990
10.3390/toxins7030648
Producción Científica
Sambucus ebulus L. (dwarf elder) is a medicinal plant, the usefulness of which also as food is restricted due to its toxicity. In the last few years, both the chemistry and pharmacology of Sambucus ebulus L. have been investigated. Among the structural and functional proteins present in the plant, sugar-binding proteins (lectins) with or without anti-ribosomal activity and single chain ribosome-inactivating proteins (RIPs) have been isolated. RIPs are enzymes (E.C. 3.2.2.22) that display N-glycosidase activity on the 28S rRNA subunit, leading to the inhibition of protein synthesis by arresting the step of polypeptide chain elongation. The biological role of all these proteins is as yet unknown. The evidence suggests that they could be involved in the defense of the plant against predators and viruses or/and a nitrogen store, with an impact on the nutritional characteristics and food safety. In this mini-review we describe all the isoforms of ebulin that have to date been isolated from dwarf elder, as well as their functional characteristics and potential uses, whilst highlighting concern regarding ebulin toxicity.
Junta de Castilla y León (Grupo de Excelencia GR106)
Universidad Complutense de Madrid (research group 950247)
application/pdf
eng
MDPI
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
© 2015 MDPI
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Dwarf Elder
Saúco menor
Lectin
Lectina
Ebulin
Ebulina
Ricin
Ricina
Ebulin from dwarf elder (Sambucus ebulus L.): A mini-review
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
https://www.mdpi.com/2072-6651/7/3/648
SI