2024-03-28T20:29:26Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/289472021-06-24T07:42:18Zcom_10324_1187com_10324_931com_10324_894com_10324_28542com_10324_952col_10324_1408col_10324_28543
Recyclable Chiral Bifunctional Thioureas Derived from [60]Fullerene and Their Use as Highly Efficient Organocatalysts for the Asymmetric Nitro-Michael Reaction
Andrés García, José María
González Pérez, Miguel
Maestro Fernández, Alicia
Naharro, Daniel
Pedrosa Sáez, Rafael
Catálisis
Química orgánica
Producción Científica
Three novel fullerothioureas derived from natural valine, phenylalanine, and tert-leucine have been prepared by Prato's reaction of [60]fullerene and the corresponding aldehydes. These hybrids have been used as organocatalysts in a typical stereoselective nitro-Michael addition reaction under homogeneous and neat conditions. The catalysts are easily recoverable by filtration, and are recyclable for at least five times. The addition products were obtained in excellent yields and stereoselectivities by using catalyst loadings of as low as 0.5 mol-%.
2018-07-07
Ministerio de Economía, Industria y Competitividad (Project CTQ2014-59870-P)
2018-03-12T10:18:36Z
2018-07-07T23:40:45Z
2017
info:eu-repo/semantics/article
European Journal of Organic Chemistry, 2017, Volume 2017, Issue 19, Pages 2683–2691
1434-193X
http://uvadoc.uva.es/handle/10324/28947
10.1002/ejoc.201601640
eng
http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201601640/full
Attribution-NonCommercial-NoDerivatives 4.0 International
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
application/pdf
Wiley
https://uvadoc.uva.es/bitstream/10324/28947/6/Recyclable-Eur-J-Org-Chem-2017-postprint.pdf.jpg
Hispana
TEXT
http://creativecommons.org/licenses/by-nc-nd/4.0/
UVaDOC. Repositorio Documental de la Universidad de Valladolid
http://uvadoc.uva.es/handle/10324/28947