2024-03-29T07:01:23Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/528142022-04-07T20:51:05Zcom_10324_32522com_10324_952com_10324_894col_10324_32523
Intestinal fructose and glucose metabolism in health and disease
Merino Antolín, Beatriz
Fernández Díaz, Cristina María
Cózar Castellano, Irene
Perdomo Hernández, Germán
Fructose
Fructosa
Glucose
Glucosa
Intestine
Intestino
Producción Científica
The worldwide epidemics of obesity and diabetes have been linked to increased sugar consumption in humans. Here, we review fructose and glucose metabolism, as well as potential molecular mechanisms by which excessive sugar consumption is associated to metabolic diseases and insulin resistance in humans. To this end, we focus on understanding molecular and cellular mechanisms of fructose and glucose transport and sensing in the intestine, the intracellular signaling effects of dietary sugar metabolism, and its impact on glucose homeostasis in health and disease. Finally, the peripheral and central effects of dietary sugars on the gut–brain axis will be reviewed.
Ministerio de Economía, Industria y Competitividad (grants SAF2016-77871-C2-1-R and SAF2016-77871-C2-2-R)
Fundación La-Caixa - Fundación Caja de Burgos (grant CAIXA-UBU001)
2022-04-07T11:51:24Z
2022-04-07T11:51:24Z
2020
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Nutrients, 2020, vol. 12, n. 1, 94
2072-6643
https://uvadoc.uva.es/handle/10324/52814
10.3390/nu12010094
eng
https://www.mdpi.com/2072-6643/12/1/94
Atribución 4.0 Internacional
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
© 2020 The Authors
application/pdf
MDPI
https://uvadoc.uva.es/bitstream/10324/52814/4/Intestinal-fructose-glucose-metabolism.pdf.jpg
Hispana
TEXT
http://creativecommons.org/licenses/by/4.0/
UVaDOC. Repositorio Documental de la Universidad de Valladolid
https://uvadoc.uva.es/handle/10324/52814