2026-07-22T08:21:54Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/525342025-02-06T10:59:04Zcom_10324_1166com_10324_931com_10324_894col_10324_1338

00925njm 22002777a 4500 dc Matei, Petruta Mihaela author Iacomi, Beatrice Michaela author Martín Gil, Jesús author Pérez Lebeña, Eduardo author Ramos Sánchez, María del Carmen author Barrio Arredondo, María Teresa author Martín Ramos, Pablo author 2018 Fusarium culmorum is a soil-borne fungus able to cause Fusarium head blight, one of the most important cereal diseases worldwide, which can result in significant yield losses of up to 50% and which jeopardizes food and feed safety due to the mycotoxins produced. In the study presented herein, the enhancement of the antifungal activity against this pathogen, resulting from the addition of silver nanoparticles (AgNPs) to different polyphenol-stevioside inclusion compounds, dispersed either in a chitosan oligomers hydroalcoholic solution or in a choline chloride:urea:glycerol deep eutectic solvent, was investigated in vitro. The polyphenols assayed were curcumin, ferulic acid, gallic acid and silymarin. Four composite concentrations (62.5, 125, 250 and 500 µg·mL−1), with and without AgNPs, were assessed, finding noticeable differences in mycelial growth inhibition, with EC50 and EC90 values ranging from 118 to 579 µg·mL−1 and from 333 to 2604 µg·mL−1, respectively. The obtained results evidenced the improved efficacy of the composites with AgNPs, a superior performance of the composites based on curcumin and ferulic acid, and the advantages of the deep eutectic solvent-based dispersion medium over the chitosan oligomers-based one. The reported composites hold promise for crop protection applications. Agronomy, 2018, vol. 8, n. 11, p. 239 2073-4395 https://uvadoc.uva.es/handle/10324/52534 10.3390/agronomy8110239 239 11 Agronomy 8 2073-4395 In vitro antifungal activity of composites of AgNPs and polyphenol inclusion compounds against Fusarium culmorum in different dispersion media