2024-03-28T16:53:08Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/530352023-04-21T11:03:50Zcom_10324_1133com_10324_931com_10324_894col_10324_1209
00925njm 22002777a 4500
dc
Herrera Gómez, Francisco Magno
author
Gutiérrez Abejón, Eduardo
author
Ayestarán Martínez, Ignacio José
author
Criado Espegel, Paloma
author
Álvarez González, Francisco Javier
author
2019
Opioids are driving-impairing medicines (DIM). To assess the evolution and trends of opioid analgesics use between 2015 and 2018 in Castile and Leon (Spain), a population-based registry study was conceived. The length of opioid use and its concomitant use with other DIMs were studied. Analyses were done considering age and gender distributions. Adjusted consumption for licensed drivers is also presented. Of the 5 million dispensations recorded between 2015 and 2018, opioid analgesics were dispensed to 11.44% of the general population and 8.72% of vehicle drivers. Increases among daily users (2.6 times higher) and chronic users (1.5% higher) were noted, supporting the overall increase in opioid use (1.5%). The use of multiple drugs including other DIMs was a common finding (mean ± SD, 2.54 ± 0.01). Acute use (5.26%) and chronic use (3.20%) were also frequent. Formulations combining opioid analgesics with nonopioid analgesics were preferred. The use of opioids increased in Spain between 2015 and 2018. Concomitant use with other DIMS especially affects women and the elderly. Frequent use of opioid analgesics with other DIMs is a serious problem for drivers and increases the risk of accidents. Promoting safe driving should be a main objective of health authorities, to be achieved by developing and implementing educational activities for healthcare professionals and patients.
Journal of Clinical Medicine, 2019, vol. 8, n. 12, 2148
2077-0383
https://uvadoc.uva.es/handle/10324/53035
10.3390/jcm8122148
The trends in opioid use in Castile and Leon, Spain: A population-based registry analysis of dispensations in 2015 to 2018