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oai:uvadoc.uva.es:10324/384522021-06-24T07:43:46Zcom_10324_28542com_10324_952com_10324_894com_10324_1187com_10324_931col_10324_28543col_10324_1408

Rodríguez Ferrer, Patricia Naharro, Daniel Maestro Fernández, Alicia Andrés García, José María Pedrosa Sáez, Rafael 2019-10-09T08:24:27Z 2019-10-09T08:24:27Z 2019 European Journal of Organic Chemistry 2019, 6539–6549 1434-193X http://uvadoc.uva.es/handle/10324/38452 10.1002/ejoc.201901327 European Journal of Organic Chemistry Four novel chiral bifunctional thiosquaramides have been prepared from cyclopentyl dithiosquarates and diamines derived from natural l‐Valine and l‐tert‐Leucine. The novel thiosquaramides have been tested as organocatalyst in the nitro‐Michael addition of 3‐substituted oxindoles to different β‐aryl‐substituted nitroalkenes. The reaction occurred easily in high yields and excellent stereoselectivities, showing that the novel organocatalysts are much more effective than their thioureas and squaramides homologs. eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ © Wiley Attribution-NonCommercial-NoDerivatives 4.0 Internacional Química orgánica Chiral Bifunctional Thiosquaramides as Organocatalysts in the Synthesis of Enantioenriched 3,3-Disubstituted Oxindoles info:eu-repo/semantics/article