2024-03-29T14:00:03Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/217442021-06-23T13:27:32Zcom_10324_1191com_10324_931com_10324_894col_10324_1379
Analysis of the Non-stationarity of Neural Activity during an Auditory Oddball Task in Schizophrenia
Núñez Novo, Pablo
Poza Crespo, Jesús
Gómez Pilar, Javier
Bachiller Matarranz, Alejandro
Gómez Peña, Carlos
Lubeiro Juárez, Alba
Molina Rodríguez, Vicente
Hornero Sánchez, Roberto
Schizophrenia
Producción Científica
The aim of this study was to characterize brain
dynamics during an auditory oddball task. For this purpose, a
measure of the non-stationarity of a given time-frequency
representation (TFR) was applied to electroencephalographic
(EEG) signals. EEG activity was acquired from 20
schizophrenic (SCH) patients and 20 healthy controls while
they underwent a three-stimulus auditory oddball task. The
Degree of Stationarity (DS), a measure of the non-stationarity
of the TFR, was computed using the continuous wavelet
transform. DS was calculated for both the baseline [-300 0] ms
and active task [150 550] ms windows of a P300 auditory
oddball task. Results showed a statistically significant increase
(p<0.05) in non-stationarity for controls during the cognitive
task in the central region, while less widespread statistically
significant differences were obtained for SCH patients,
especially in the beta-2 and gamma bands. Our findings
support the relevance of DS as a means to study cerebral
processing in SCH. Furthermore, the lack of statistically
significant changes in DS for SCH patients suggests an
abnormal reorganization of neural dynamics during an oddball
task.
Ministerio de Economía y Competitividad (TEC2014-53196-R)
Junta de Castilla y León (VA059U13)
2016-12-15T06:54:56Z
2016-12-15T06:54:56Z
2016
info:eu-repo/semantics/article
https://doi.org/10.1109/EMBC.2016.7591537
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2016, p. 3724 - 3727
1557-170X
http://uvadoc.uva.es/handle/10324/21744
eng
http://ieeexplore.ieee.org/servlet/opac?punumber=1000269
Attribution-NonCommercial-NoDerivatives 4.0 International
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
application/pdf
IEEE Conference Publications