2024-03-28T12:42:41Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/314432021-06-24T07:46:34Zcom_10324_31661com_10324_952com_10324_894com_10324_23040com_10324_954col_10324_31662col_10324_23041
Production of copper loaded lipid microparticles by PGSS® (particles from gas saturated solutions) process
Martín, Victor
Gonçalves, Vanessa Santos Silva
Rodríguez Rojo, Soraya
Nunes, Daniela
Fortunato, Elvira
Martins, Rodrigo
Cocero Alonso, María José
Duarte, Catarina M.M.
Production of lipid particles loaded with metal nanoparticles by supercritical fluids based processes has been barely studied. In this work, copper nanoparticles were loaded into glyceryl palmitostearate microparticles by PGSS® (Particles from Gas Saturated Solutions). The effect of different variables, temperature (60-80 ºC), copper load (0.2-5%w/w) and water addition (0 – 40%w/w), in particle size and encapsulation efficiency has been studied. The dispersion of metal nanoparticles in the lipid has been determined by SEM-FIB coupled with EDS mapping. In all cases, mean particle size values lower than 70 μm have been obtained, and encapsulation efficiencies around 60% have been achieved. The addition of water has no negative effect in encapsulation efficiency nor in nanoparticles dispersion within the lipid microparticle, being important since nanoparticles are commonly synthetized in aqueous medium.
2018-09-07T08:51:00Z
2018
info:eu-repo/semantics/article
The Journal of Supercritical Fluids, 2018, vol.131, p. 124–129.
http://uvadoc.uva.es/handle/10324/31443
http://dx.doi.org/10.1016/j.supflu.2017.09.001
eng
https://www.sciencedirect.com/science/article/pii/S0896844617303790
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
Elsevier B.V.
SI