RT info:eu-repo/semantics/masterThesis
T1 A new method for detection of cyclic circadian genes using order restricted inference
A1 Larriba González, Yolanda
A2 Universidad de Valladolid. Facultad de Ciencias
K1 Algoritmo JTK Cycle
K1 Ciclo circadiano - Expresión génica
AB Identification of periodic patterns in gene expression data is important for studyingthe regulation mechanism of the circadian system. The information available isoften given only by one or two cycles. Consequently, the number of observations isnot enough to fit certain models, such as Fourier's models, properly. Some authorshave already developed procedures or algorithms among which the JTK CYCLEalgorithm is the most popular one.We propose a new method to identify cyclic gene expressions based on euclideanand circular order restricted inference. Validation of the method is made throughreal data sets and simulations. Moreover, we compare the results obtained by themethod with other detecting methods developed in the literature.
YR 2015
FD 2015
LK http://uvadoc.uva.es/handle/10324/13529
UL http://uvadoc.uva.es/handle/10324/13529
LA eng
NO Departamento de Estadística e Investigación Operativa
DS UVaDOC
RD 21-nov-2024