RT info:eu-repo/semantics/article T1 Multi-Stencil Streamline Fast Marching: a general 3D Framework to determine Myocardial Thickness and Transmurality in Late Enhancement Images A1 Merino Caviedes, Susana A1 Cordero Grande, Lucilio A1 Revilla Orodea, Ana A1 Sevilla Ruiz, María Teresa A1 Pérez García, María Teresa A1 Martín Fernández, Marcos Antonio A1 Alberola López, Carlos K1 Perfusion imaging K1 heart K1 quantification and estimation K1 myocardial viability K1 transmurality K1 fast marching AB We propose a fully three-dimensional methodologyfor the computation of myocardial non-viable tissue transmuralityin contrast enhanced magnetic resonance images. The outcomeis a continuous map defined within the myocardium where notonly current state-of-the-art measures of transmurality can becalculated, but also information on the location of non-viabletissue is preserved. The computation is done by means of apartial differential equation framework we have called Multi-Stencil Streamline Fast Marching (MSSFM). Using it, the myocardialand scarred tissue thickness is simultaneously computed.Experimental results show that the proposed 3D method allowsfor the computation of transmurality in myocardial regions wherecurrent 2D methods are not able to as conceived, and it alsoprovides more robust and accurate results in situations where theassumptions on which current 2D methods are based —i.e., thereis a visible endocardial contour and its corresponding epicardialpoints lie on the same slice—, are not met. YR 2014 FD 2014 LK http://uvadoc.uva.es/handle/10324/15157 UL http://uvadoc.uva.es/handle/10324/15157 LA spa NO IEEE Transactions on Medical Imaging, Vol. 33, No. 1, pp. 23-37, Enero 2014. DS UVaDOC RD 27-jul-2024