RT info:eu-repo/semantics/article
T1 Improvement of electrocatalytic effect in voltammetric sensors based on phthalocyanines
A1 Rodríguez Méndez, María Luz
A1 Medina Plaza, Cristina
A1 García Hernández, Celia
A1 Rodríguez, Silvia
A1 García Cabezón, Ana Cristina
A1 Paniagua Albillos, David
A1 Rodríguez Pérez, Miguel Ángel
A1 Saja Sáez, José Antonio de
K1 Voltammetric sensors
K1 Phthalocyanine
K1 Bisphthalocyanine
K1 Phenols
K1 Nanoparticles
K1 Biosensors
AB Voltammetric sensors based on phthalocyanines have been used to detect a variety of compounds. In this paper, the state of the art of sensors prepared using classical techniques will be revised. Then, new strategies to improve the performance of the sensors will be described using as example sensors chemically modified with lutetium bisphthalocyanine (LuPc2) dedicated to the detection of phenols of interest in the food industry. Classical LuPc2 carbon paste electrodes can detect phenols such as catechol, caffeic acid or pyrogallol with limits of detection in the range of 10-4–10-5 M. The performance can be improved by using nanostructured Langmuir–Blodgett (LB) or Layer by Layer (LbL) films. The enhanced surface to volume ratio produce an increase in the sensitivity of the sensors. Limits of detection of 10-5–10-7 M are attained, which are one order of magnitude lower than those obtained using conventional carbon paste electrodes. Moreover, these techniques can be used to coimmobilize two electrocatalytic materials in the same device. The limits of detection obtained in LB sensors combining LuPc2/AuNPs or LuPc2/CNT are further improved. Finally, the LB technique has been used to prepare biosensors where a phenol oxydase (such as tyrosinase or lacasse) is immobilized in a biomimetic environment that preserves the enzymatic activity. Moreover, LuPc2 can be co-immobilized with the enzyme in a lipidc film formed by arachidic acid (AA). LuPc2 can act as an electron mediator facilitating the electron transfer. These biomimetic sensors formed by LuPc2/AA/enzyme show Limits of detection of 10-8 M and an enhanced selectivity.
PB World Scientific
SN 1088-4246
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/21092
UL http://uvadoc.uva.es/handle/10324/21092
LA eng
NO Journal of Porphyrins and Phthalocyanines, Enero 2016, vol. 20, p. 1-8
NO Producción Científica
DS UVaDOC
RD 22-dic-2024