RT info:eu-repo/semantics/article
T1 Supported bifunctional thioureas as recoverable and reusable catalysts for enantioselective nitro-Michael reactions
A1 Andrés García, José María
A1 Ceballos, Miriam
A1 Maestro Fernández, Alicia
A1 Sanz, Isabel
A1 Pedrosa Sáez, Rafael
K1 Catalizadores
AB The catalytic activity of different supported bifunctional thioureas on sulfonylpolystyrene resins has been studied in the nitro-Michael addition of different nucleophiles to trans-β-nitrostyrene derivatives. The activity of the catalysts depends on the length ofthe tether linking the chiral thiourea to the polymer. The best results were obtained with the thiourea derived from (L)-valine and1,6-hexanediamine. The catalysts can be used in only 2 mol % loading, and reused for at least four cycles in neat conditions. Theball milling promoted additions also worked very well.
PB Beilstein-Institut
SN 1860-5397
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/21443
UL http://uvadoc.uva.es/handle/10324/21443
LA eng
NO Beilstein Journal of Organic Chemistry, 2016, 12, p. 628–635
NO Producción Científica
DS UVaDOC
RD 24-nov-2024