RT info:eu-repo/semantics/article
T1 Analysis of the Non-stationarity of Neural Activity during an Auditory Oddball Task in Schizophrenia
A1 Núñez Novo, Pablo
A1 Poza Crespo, Jesús
A1 Gómez Pilar, Javier
A1 Bachiller Matarranz, Alejandro
A1 Gómez Peña, Carlos
A1 Lubeiro Juárez, Alba
A1 Molina Rodríguez, Vicente
A1 Hornero Sánchez, Roberto
K1 Schizophrenia
AB The aim of this study was to characterize braindynamics during an auditory oddball task. For this purpose, ameasure of the non-stationarity of a given time-frequencyrepresentation (TFR) was applied to electroencephalographic(EEG) signals. EEG activity was acquired from 20schizophrenic (SCH) patients and 20 healthy controls whilethey underwent a three-stimulus auditory oddball task. TheDegree of Stationarity (DS), a measure of the non-stationarityof the TFR, was computed using the continuous wavelettransform. DS was calculated for both the baseline [-300 0] msand active task [150 550] ms windows of a P300 auditoryoddball task. Results showed a statistically significant increase(p<0.05) in non-stationarity for controls during the cognitivetask in the central region, while less widespread statisticallysignificant differences were obtained for SCH patients,especially in the beta-2 and gamma bands. Our findingssupport the relevance of DS as a means to study cerebralprocessing in SCH. Furthermore, the lack of statisticallysignificant changes in DS for SCH patients suggests anabnormal reorganization of neural dynamics during an oddballtask.
PB IEEE Conference Publications
SN 1557-170X
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/21744
UL http://uvadoc.uva.es/handle/10324/21744
LA eng
NO Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2016, p. 3724 - 3727
NO Producción Científica
DS UVaDOC
RD 28-dic-2024