RT info:eu-repo/semantics/doctoralThesis
T1 Bioproducts processing by Sfee: application for liquid and solid Quercetin formulations
A1 Lévai, György
A2 Universidad de Valladolid. Escuela de Ingenierías Industriales
K1 Procesos químicos
K1 Quercetina - Notación
K1 Flavonoides|
AB Quercetin is a member of flavonoids, which is the major group of the polyphenols, and is highly available in various fruits, vegetables and oils. It has an anti-proliferative effect in a wide range of human cancer cell lines, and it is a highly promising active compound against a wide variety of diseases. A major limitation for the clinical application of quercetin is its low bioavailability (lower than 1% in humans), due to its low water solubility, which makes necessary to administrate it in doses, as high as 50 mg/kg.Supercritical fluid technologies are promising alternative in the processing of natural bioactive compounds like quercetin, because upon applying an adequate supercritical medium such as supercritical carbon-dioxide (scCO2), they allow carrying out the encapsulation process at near ambient temperatures and in an inert atmosphere, thus avoiding the thermal degradation or oxidation of the product, and reducing its contamination with organic solvents.
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/22227
UL http://uvadoc.uva.es/handle/10324/22227
LA eng
NO Departamento de Ingeniería Química y Tecnología del Medio Ambiente
DS UVaDOC
RD 06-ago-2024