RT info:eu-repo/semantics/conferenceObject
T1 Estimating and testing circular orders for cell cycle genes expression data
A1 Rueda Sabater, María Cristina
A1 Fernández Temprano, Miguel Alejandro
A1 Barragán, Sandra
A1 Peddada, Shyamal
AB Analysis of angular data has a long history with well-developed theory and methodology documented in several books [cf. Fisher (1993), Mardia and Jupp (2000)]. Most of the theory have been developed several decades ago. However, in recent years, and motivated by the applications, there has been a reawaked interest in drawing inferences regarding angular parameters. In particular, in the biology field to analyze periodic patterns of gene expressions. These patterns show the contribution of the genes in oscillatory biological processes, such as the cell-cycle, the circadian clock or the metabolic cycle. The time to peak expression (known as the phase angle) of such a gene can be mapped onto a unit circle and is an angular parameter.
YR 2013
FD 2013
LK http://uvadoc.uva.es/handle/10324/22924
UL http://uvadoc.uva.es/handle/10324/22924
LA eng
DS UVaDOC
RD 27-nov-2024