RT info:eu-repo/semantics/conferenceObject
T1 A new method for identification of cyclic circadian genes using circular isotonic regression.
A1 Larriba González, Yolanda
A1 Rueda Sabater, María Cristina
A1 Fernández Temprano, Miguel Alejandro
AB Identification of periodic patterns in gene expression data is important for studying the regulation mechanism of the circadian system. The information available is often given only by one or two cycles. Consequently, the number of observations is not enough to fit certain models, such as Fourier's models, properly. Some authors have already developed procedures or algorithms among which the JTK\_Cycle algorithm is the most popular one.We propose a new method to identify cyclic gene expressions based on circular order restricted inference. Validation of the method is made through real data sets and simulations. Moreover, we compare the results obtained by the method with other detecting methods developed in the literature.
YR 2015
FD 2015
LK http://uvadoc.uva.es/handle/10324/22933
UL http://uvadoc.uva.es/handle/10324/22933
LA eng
DS UVaDOC
RD 24-nov-2024