RT info:eu-repo/semantics/bookPart T1 Ca2 + Dynamics in chemoreceptor cells: an overview A1 González, Constancio A1 Rocher Martín, María Asunción A1 Obeso Cáceres, Ana María de la Luz A1 López López, José Ramón A1 García-Sancho Martín, Francisco Javier K1 Cuerpo carotídeo K1 Células hemorreceptoras AB The carotid body (CB) was defined as a sensory organ by De Castro in 1928. Two years later, Heymanns and coworkers demostrated that the organ was sensitive to alterations in blood gases and pH, in such a way that a decrease in blood P02 or pH or an increase in blood PC02 produced activation of the CB and, reflexely, hyperventilation. De Castro postulated that glomus cells were the sensor structures and that they should release sorn substance to transmit the stimulus to the sensory nerve endings (De Castro, 1928). De Castro's point of view, was widely accepted, and therefore the CB wasconsidered a secondary sensory receptor. As a consequence, the principal aims of many workers in the chemoreception field have been to define the nature of the sensing mechanims ( sensory transduction process ) and to identify the substances released by chern cells. PB Plenum Press YR 1993 FD 1993 LK http://uvadoc.uva.es/handle/10324/24947 UL http://uvadoc.uva.es/handle/10324/24947 LA eng NO Data, P.G. (coord.) Neurobiology and Cell Physiology of Chemoreception. New York: Plenum Press, 1993, p.149-156 NO Producción Científica DS UVaDOC RD 29-mar-2024