RT info:eu-repo/semantics/article
T1 Carbon Monoxide inhibits hypoxic pulmonary vasoconstriction in rats by a cGMP-independent mechanism
A1 Tamayo Lomas, Luis Mariano
A1 López López, José Ramón
A1 Castañeda, Javier
K1 Monóxido de carbono
K1 Hypoxia
K1 Arteria pulmonar
AB Hypoxia activates erythropoietin-producing cells, chemoreceptor cells of the carotid body and pul- monary artery smooth muscle cells (PSMC) with a com- Key words  Hypoxia · Pulmonary artery · Carbon monoxide&bdy: parable arterial PO2  threshold of some 70 mmHg. The	 	 inhibition by CO of the hypoxic responses in the two for- mer cell types has led to the proposal that a haemopro- tein is involved in the detection of the PO2 levels. Here, we report the effect of CO on the hypoxic pulmonary va- soconstriction (HPV). Pulmonary arterial pressure (PAP)was measured in an in situ, blood-perfused lung prepara- tion.   PAP   in   normoxia   (20%   O2,   5%   CO2) .
PB Springer Verlag
SN 0031-6768
YR 1997
FD 1997
LK http://uvadoc.uva.es/handle/10324/25327
UL http://uvadoc.uva.es/handle/10324/25327
LA eng
NO Pflügers Arch - Eur J. Physiol (1997)
NO Producción Científica
DS UVaDOC
RD 22-nov-2024