RT info:eu-repo/semantics/article
T1 Multiresidue analytical method for pharmaceuticals and personal care products in sewage and sewage sludge by online direct immersion SPME on-fiber derivatization – GCMS
A1 López Serna, Rebeca
A1 Marín de Jesús, David Fernando
A1 Irusta Mata, Rubén
A1 García Encina, Pedro Antonio
A1 Lebrero Fernández, Raquel
A1 Fernández-Polanco Íñiguez de la Torre, María
A1 Muñoz Torre, Raúl
K1 Aguas residuales
K1 Productos farmaceúticos
AB The work here presented aimed at developing an analytical method for the simultaneous determination of 22 pharmaceuticals and personal care products, including 3 transformation products, in sewage and sludge. A meticulous method optimization, involving an experimental design, was carried out. The developed method was fully automated and consisted of the online extraction of 17 mL of water sample by Direct Immersion Solid Phase MicroExtraction followed by On-fiber Derivatization coupled to Gas Chromatography – Mass Spectrometry (DI-SPME – On-fiber Derivatization – GC – MS). This methodology was validated for 12 of the initial compounds as a reliable (relative recoveries above 90% for sewage and 70% for sludge; repeatability as %RSD below 10% in all cases), sensitive (LODs below 20 ng L−1 in sewage and 10 ng g−1 in sludge), versatile (sewage and sewage-sludge samples up to 15,000 ng L−1 and 900 ng g−1, respectively) and green analytical alternative for many medium-tech routine laboratories around the world to keep up with both current and forecast environmental regulations requirements. The remaining 10 analytes initially considered showed insufficient suitability to be included in the final method. The methodology was successfully applied to real samples generated in a pilot scale sewage treatment reactor.
PB Elsevier
SN 0039-9140
YR 2018
FD 2018
LK http://uvadoc.uva.es/handle/10324/31394
UL http://uvadoc.uva.es/handle/10324/31394
LA eng
NO Talanta Volume 186, 2018, Pages 506-512
NO Producción Científica
DS UVaDOC
RD 07-ago-2024