RT info:eu-repo/semantics/masterThesis T1 Prevalence of TERT promoter mutations in Anaplastic Thiroid Carcinomas. Concurrent activation of TERT and MAPK signalling pathway A1 Rodríguez García, María de los Ángeles (Facultad de Medicina) A2 Universidad de Valladolid. Facultad de Medicina K1 Oncología K1 Tiroides AB As it is known, cancer is defined as an uncontrolled growth of cells in a located part of the body.The problem starts when, from a normal division of cells, an alteration occurs that provokes thisabnormal growth, and ends in a mass of cells (Tumour). It can occur that the system actsrepairing this situation, by causing apoptosis in those transformed cells, so they would die.However, in case the damage cannot be repaired, they would keep on growing and invadingother organs or tissues leading to local or distant metastasis YR 2018 FD 2018 LK http://uvadoc.uva.es/handle/10324/31619 UL http://uvadoc.uva.es/handle/10324/31619 LA spa DS UVaDOC RD 03-mar-2025