RT info:eu-repo/semantics/article
T1 Zinc Nutritional Status in Patients with Cystic Fibrosis
A1 Escobedo Monge, Marlene Fabiola
A1 Barrado Esteban, Enrique
A1 Alonso Vicente, Carmen
A1 Redondo del Río, María Paz
A1 Marugán de Miguelsanz, José Manuel
K1 serum zinc concentration; hypozincemia; dietary zinc intake; dietary zinc deficiency; cystic fibrosis; marginal zinc deficiency
AB Background: Zinc is an essential nutrient for all forms of life and its deficiency affects thenormal growth and development of human beings. Objective: The main aim was to investigate zincnutritional status by serum zinc concentration (SZC) and dietary zinc intake and their associationin cystic fibrosis (CF) patients. Methods: A cross-sectional study was conducted in CF patients.Anthropometric measurements and respiratory and pancreatic tests were conducted.Hypozincemia was determined by SZC while using atomic absorption spectrophotometry anddietary zinc deficiency by prospective 72-h dietary surveys. Results: Mean SZC (87.2 ± 16.7 μg/dL)and dietary zinc intake (97 ± 26.9% Dietary Reference Intake) were normal. Three of 17 patientswith CF (17.6%) had hypozincemia and four (23.5%) had a dietary zinc deficiency. No patient withdietary zinc deficiency had hypozincemia. A positive and significant association was observedbetween SZC and Z-score of BMI-for-age (p = 0.048) and weight-for-height (p = 0.012) and betweendietary zinc intake and energy intake (EI, p = 0.036) and Z-score of weight-for-high (p = 0.029).Conclusion: SZC was associated with the nutritional status, expressed as BMI (Body Mass Index)and weight-for-height Z score, and dietary zinc intake with EI and weight-for-height Z-score. Nopatient with hypozincemia had dietary zinc deficiency. This situation should alert us to a marginalzinc deficiency and it may explain why there were no overlapping cases between the two groups.We suggest that probably 41% of the cases in this study would be at elevated risk of zinc deficiencyand a zinc supplementation may be considered.
PB MDPI
SN 2072-6643
YR 2019
FD 2019
LK http://uvadoc.uva.es/handle/10324/38727
UL http://uvadoc.uva.es/handle/10324/38727
LA eng
NO NUTRIENTS, 2019, 11, 150
NO Producción Científica
DS UVaDOC
RD 11-jul-2024