RT info:eu-repo/semantics/article
T1 Supported Bifunctional Chiral Thioureas as Catalysts in the Synthesis of 3‐Amino‐2‐Oxindoles through Enantioselective aza‐Friedel‐Crafts Reaction: Application in Continuous Flow Processes
A1 Rodríguez Rodríguez, Marta
A1 Maestro Fernández, Alicia
A1 Andrés García, José María
A1 Pedrosa Sáez, Rafael
K1 Catálisis asimétrica
K1 Asymmetric catalysis
K1 23 Química
AB Supported cinchone‐derived thioureas promote highly enantioselective aza‐Friedel‐Crafts reaction of different naphthols with a variety of N‐Boc ketimines derived from isatin. The catalysts are recoverable and reusable, and one of the supported catalysts has been used in a flow process allowing the synthesis of 3‐amino‐2‐oxindole derivatives in multigram scale with high yield and enantioselectivity.
PB Wiley
SN 1615-4150
YR 2020
FD 2020
LK http://uvadoc.uva.es/handle/10324/40885
UL http://uvadoc.uva.es/handle/10324/40885
LA eng
NO Advanced Synthesis & Catalysis, 2020, 362, 1 –12
NO Producción Científica
DS UVaDOC
RD 22-nov-2024