RT info:eu-repo/semantics/article T1 Silver nanoparticles embedded in natural rubber films: synthesis, characterization and evaluation of in vitro toxicity A1 Danna, Caroline Silva A1 Cavalcante, Dalita Gomes Silva Morais A1 Gomes, Andressa S. A1 Ernst Kerche, Leandra A1 Kerche Silva, Leandra Ernst A1 Yoshihara, Eidi A1 Osorio Román, Igor A1 Salmazo, Leandra A1 Rodríguez Pérez, Miguel Ángel A1 Aroca, Ricardo A1 Job, Aldo Eloizo K1 Silver nanoparticles K1 Nanopartículas de plata K1 In vitro toxicity K1 Toxicidad in vitro K1 Natural rubber films K1 Recubrimientos de goma natural AB Natural rubber (NR) films can reduce silver metal ions forming embedded metal nanoparticles, a process that could be described as green synthesis. The NR films acting as a reactor generate and incorporate silver nanoparticles (AgNPs). Organic acids and amino acids play a crucial role in the formation of AgNPs. The plasmon extinction obtained in the UV-visible spectrum shows the presence of nanoparticles in the film after dipping the NR film into a solution of silver nitrate at 80°C. Electron microscopic analysis confirms the presence of AgNPs in the NR film and characterization by atomic force microscopy shows a change in the roughness of the NR film with AgNPs. In addition, our preliminary results from in vitro toxicity studies (MTT and comet assays) of the NR films and NR films with silver nanoparticles (NR/Ag) show that they are not toxic to cell lineage CHO-K1 (cells from the ovary of a Chinese hamster), an important result for potential medical applications. PB Hindawi SN 1687-4110 YR 2016 FD 2016 LK http://uvadoc.uva.es/handle/10324/40981 UL http://uvadoc.uva.es/handle/10324/40981 LA eng NO Journal of Nanomaterials, 2016, vol. 2016. 10 p. NO Producción Científica DS UVaDOC RD 22-dic-2024