RT info:eu-repo/semantics/article
T1 Deuterium Exchange between Arenes and Deuterated Solvents in the Absence of a Transition Metal: Synthesis of D-Labeled Fluoroarenes
A1 Salamanca Verdugo, Vanesa
A1 Albéniz Jiménez, Ana Carmen
K1 Deuteration
K1 H/D exchange
K1 Isotope labeling
K1 Fluoroarenes
K1 C–H activation
AB Fluoroarenes can be selectively deuterated by H/D exchange with common deuterated solvents in the presence of a catalytic amount of an alkali metal carbonate or, for the less acidic arenes, stoichiometric quantities of potassium phosphate. This is a sustainable method that does not need transition metal catalysis or the multistep synthesis of a main-group orga- nometallics. This exchange needs to be taken into account when using H/D scrambling as a mechanistic probe in reactions involving fluoroarenes.
PB Wiley-VCH
SN 1434-193X
YR 2020
FD 2020
LK http://uvadoc.uva.es/handle/10324/42936
UL http://uvadoc.uva.es/handle/10324/42936
LA eng
NO Eur. J. Org. Chem. 2020, 3206–3212
NO Producción Científica
DS UVaDOC
RD 11-dic-2024