RT info:eu-repo/semantics/article T1 Búsqueda de perfiles genéticos de susceptibilidad heredada a obesidad severa A1 Rodríguez López, Raquel A1 Albuquerque do Santos, David A1 Gimeno Ferrer, Fátima A2 Ediciones Universidad de Valladolid AB Obesity is considered today as a global epidemic of a chronic disease that generates an abnormal or excessive accumulation of fat, which in a significant percentage of patients appears from very early ages and a large part of life is maintained. In addition to the direct and indirect costs that it causes, it is a serious prejudice to the quality of life and health of the individuals affected. In general, it is widely accepted that both genes and the environment participate in the constitution and maintenance of body weight. It has been estimated that hereditary factors participate between 40 and 70% of individual susceptibility to the onset of obesity.However, our knowledge about the genetic bases associated with the development of a serious and intractable overweight, remains negligible. Our Group of the Genomics Laboratory of the Research Foundation of the General University Hospital of Valencia, has the opportunity to present our main line of research to all the academics, collaborators and assistants of the Royal Academy of Medicine of Valladolid. The possibility of presenting and receiving the opinion of such a multidisciplinary team of professionals with great experience in the health field, has allowed us to contrast the strategy we have designed to direct our activity in the study and identification of the genetic predisposition to obesity. We have maintained for a decade, the firm objective of demonstrating and characterizing the existence of inherited and transmissible profiles that predispose from early childhood to develop a physical aspect whose main characteristic is serious overweight. SN 0210-6523 YR 2018 FD 2018 LK http://uvadoc.uva.es/handle/10324/44532 UL http://uvadoc.uva.es/handle/10324/44532 LA spa NO Anales de la Real Academia de Medicina y Cirugía de Valladolid, 2018, N.55, pags.59-69 DS UVaDOC RD 01-may-2024