RT info:eu-repo/semantics/article
T1 The FASTK family of proteins : emerging regulators of mitochondrial RNA biology
A1 Jourdain, Alexis A.
A1 Popow, Johannes
A1 Fuente García, Miguel Ángel de la
A1 Martinou, Jean-Claude
A1 Anderson, Paul
A1 Simarro Grande, María
K1 Mitochondrial RNA
K1 ARN mitocondrial
K1 Proteins
K1 Proteínas
AB The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention.
PB Oxford University Press
SN 1362-4962
YR 2017
FD 2017
LK http://uvadoc.uva.es/handle/10324/44624
UL http://uvadoc.uva.es/handle/10324/44624
LA eng
NO Nucleic Acids Research, 2017, vol. 45, n. 19. p. 10941-10947
NO Producción Científica
DS UVaDOC
RD 18-nov-2024