RT info:eu-repo/semantics/article T1 HIV-1 Infection in Persistently HIV-1-Seronegative Individuals: More Reasons for HIV RNA Screening A1 Ortiz de Lejarazu Leonardo, Raúl A1 Soriano, Vincent A1 Eiros Bouza, José María A1 Arias, Manuel A1 Toro, Carlos K1 VIH K1 Infección K1 Anticuerpos K1 32 Ciencias Médicas AB The World Health Organization (WHO) has recently released updated guidelines for HIV diagnosis that recommend serum antibody testing by either EIAs or rapid tests and that encourage the identification of unrecognized HIV infections [1]. However, this approach may fail to identify subjects with acute infection. In consideration of the potential public health benefits of not missing individuals in the most contagious phase of infection, implementation of routine HIV RNA screening has been suggested [2]. We want to stress that there are other situations in which viral load is detectable in the absence of reactive antibody tests and in which the introduction of nucleic acid testing may be beneficial. This is the case for HIV-infected subjects in whom specific antibody responses are absent, as for the case reported here. PB Oxford University Press SN 1058-4838 YR 2008 FD 2008 LK http://uvadoc.uva.es/handle/10324/45493 UL http://uvadoc.uva.es/handle/10324/45493 LA eng NO Clinical Infectious Diseases, 2008, vol. 46, n.5, p. 785 NO Producción Científica DS UVaDOC RD 22-dic-2024