RT info:eu-repo/semantics/article
T1 Impact of ventilator-associated pneumonia on mortality and epidemiological features of patients with secondary peritonitis
A1 Heredia Rodríguez, María
A1 Peláez, María Teresa
A1 Fierro Lorenzo, María Inmaculada
A1 Gómez Sánchez, Esther
A1 Gómez Pesquera, Estefanía
A1 Lorenzo López, Mario
A1 Álvarez González, Francisco Javier
A1 Bustamante Munguira, Juan
A1 Eiros Bouza, José María
A1 Bermejo Martín, Jesús Francisco
A1 Gómez Herreras, José Ignacio
A1 Tamayo Gómez, Eduardo
K1 Intensive care
K1 Cuidados intensivos
K1 Peritonitis
K1 Linezolid
AB Background: Despite the significant impact of nosocomial infections on the morbidity and mortality of patients staying in the intensive care unit (ICU), no study over the past 20 years has focused specifically on VAP following secondary peritonitis. The objective of the present study was to determine in-hospital mortality and epidemiological features attributed to ventilator-associated pneumonia (VAP) following secondary peritonitis. Methods: Prospective observational study involved 418 consecutive patients admitted in the ICU. Univariate and multivariate analyses were performed to identify risk factors associated with mortality and development of VAP. Results: The incidence of VAP following secondary peritonitis was 9.6 %. Risk factors associated with the development of VAP were hospital-acquired peritonitis, requiring >48 h of mechanical ventilation, and SOFA score. The onset of VAP was late in majority of patients. VAP was developed about 16.8 days after the initiation of the peritonitis. Etiological microorganisms responsible for the peritonitis were different than for VAP. The 90-day in-hospital mortality rate was 47.5 % of VAP patients. Independent factors associated with 30- to 90-day in-hospital mortality were VAP and SOFA. Conclusions: In light of the impact on morbidity and mortality in the ICU, more attention should be given to the concurrent features among VAP and secondary peritonitis.
PB Springer Open
SN 2110-5820
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/45526
UL http://uvadoc.uva.es/handle/10324/45526
LA eng
NO Annals of Intensive Care, 2016, vol. 6. 9 p.
NO Producción Científica
DS UVaDOC
RD 04-may-2024